GUT-70
CAS No. : 161633-75-6
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| Cat. No. : | HY-120923 |
| M.Wt: | 382.45 |
| Formula: | C23H26O5 |
| Purity: | >98 % |
| Solubility: |
GUT-70, a tricyclic coumarin, is a Hsp90 inhibitor. GUT-70 activates the caspase 2, 3, 8 and 9, and induces the apoptosis in leukemic cells. GUT-70 inhibits HIV-1 replication in chronically infected cells via suppression of the NF-κB pathway. GUT-70 can be used for the study of leukemic, mantle cell lymphoma (MCL) and HIV-1 infection[1][2][3].
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