4-Chlorocinnamic acid
CAS No. : 1615-02-7
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|---|---|---|
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| 500g | $80 | In-stock |
| 1000g | $134 | In-stock |
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| Cat. No. : | HY-Y0729 |
| M.Wt: | 182.61 |
| Formula: | C9H7ClO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A). 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0.477 mM and 0.229 mM, respectively. 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides. 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4].
IC50 & Target:IC50 values: 0.477 mM and 0.229 mM for monophenolase and diphenolase activities of mushroom tyrosinase, respectively
In Vitro:4-Chlorocinnamic acid inhibits both monophenolase and diphenolase activities of mushroom tyrosinase, with IC50 values of 0.477 mM and 0.229 mM, respectively[1].
4-Chlorocinnamic acid (0.5 mg/mL) inhibits the mycelial growth of Colletotrichum gloeosporioides in vitro with an inhibition rate of approximately 65%[3].
In Vivo:4-Chlorocinnamic acid (100-300 mg/kg; i.p.) exhibits anticonvulsant activity in Kunming mice with acute seizure induced by Pentylenetetrazol[4].
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