PCO371
CAS No. : 1613373-33-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | In-stock |
| 10mg | $265 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $680 | In-stock |
| 100mg | $960 | In-stock |
| 500mg | $1920 | In-stock |
| 1g | $2920 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-100856 |
| M.Wt: | 635.65 |
| Formula: | C29H32F3N5O6S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. IC50 & Target:PTHR1[1] In Vitro:PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 induces cAMP production with an EC50 of 2.4 μM in COS-7 cells expressing hPTHR1, and 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC50, 17 μM)[1].
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