Amotosalen (hydrochloride)
CAS No. : 161262-45-9
(Synonyms: S-59)
| Size | Price | Stock |
|---|---|---|
| 5mg | $400 | In-stock |
| 10mg | $680 | In-stock |
| 25mg | $1350 | In-stock |
| 50mg | $2200 | In-stock |
| 100mg | $3400 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-107004A |
| M.Wt: | 337.80 |
| Formula: | C17H20ClNO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 7.14 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD)[1][2]. In Vitro:When activated by light, Amotosalen binds to the nucleic acid of the pathogen and prevents replication. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells[1].
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