Acetaminophen glucuronide


CAS No. : 16110-10-4

(Synonyms: APAP-glu)

16110-10-4
Price and Availability of CAS No. : 16110-10-4
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Cat. No. : HY-113083
M.Wt: 327.29
Formula: C14H17NO8
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 16110-10-4 :

Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005)[1][2]. Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[3][4]. In Vitro: Acetaminophen is metabolized in the liver mainly by glucuronidation and sulfation, thus generating the nontoxic metabolites, Acetaminophen glucuronide (APAP-glu). Acetaminophen glucuronide is a substrate for both canalicular Mrp2 and basolateral Mrp3 in rodents[1].

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