Nrf2-IN-1
CAS No. : 1610022-76-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $200 | In-stock |
| 10mg | $280 | In-stock |
| 25mg | $465 | In-stock |
| 50mg | $650 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-101025 |
| M.Wt: | 383.87 |
| Formula: | C21H22ClN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 260 mg/mL (ultrasonic) |
Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML)[1].
IC50 & Target: Nrf2[1]
In Vitro: Nrf2-IN-1 (Compound 4f) (10 μM) inhibits Nrf2 activation[1].
Nrf2-IN-1(1-20 μM; 48 hours) inhibits growth of the three AML cell[1].
Nrf2-IN-1 (5-10 μM; 48 hours) induces apoptosis of three AML cells in vitro[1].
Nrf2-IN-1 induces apoptotic signaling involving Bcl-2 and Bax[1].
In Vivo: Nrf2-IN-1 inhibits tumor growth via apoptosis in chicken eggs[1].
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