| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $108 | In-stock |
| 25mg | $216 | In-stock |
| 50mg | $345 | In-stock |
| 100mg | $550 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-12401 |
| M.Wt: | 537.63 |
| Formula: | C26H31N7O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C) |
Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM. IC50 & Target: IC50: 50 nM (MPS1)[1] In Vitro: Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC50 of appr 5 µM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint[1]. In Vivo: Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity[1].
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