Mps1-IN-3


CAS No. : 1609584-72-6

1609584-72-6
Price and Availability of CAS No. : 1609584-72-6
Size Price Stock
5mg $70 In-stock
10mg $108 In-stock
25mg $216 In-stock
50mg $345 In-stock
100mg $550 In-stock
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Cat. No. : HY-12401
M.Wt: 537.63
Formula: C26H31N7O4S
Purity: >98 %
Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1609584-72-6 :

Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM. IC50 & Target: IC50: 50 nM (MPS1)[1] In Vitro: Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC50 of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC50 of appr 5 µM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint[1]. In Vivo: Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity[1].

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