Diethyl pyrocarbonate


CAS No. : 1609-47-8

1609-47-8
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Cat. No. : HY-D0846
M.Wt: 162.14
Formula: C6H10O5
Purity: >98 %
Solubility: H2O : ≥ 33.33 mg/mL;DMSO : 100 mg/mL (ultrasonic)
Introduction of 1609-47-8 :

Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling[1]. In Vivo:Diethyl pyrocarbonate (220 mg/kg, i.g., twice a week for 4 weeks) combined with ammonia (42 mg/kg) induces lung tumours in HSL, HSS, Kid: CFLP and Lati: CFLP mice[2].

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