BW-723C86
CAS No. : 160521-72-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $170 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $950 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-101369 |
| M.Wt: | 322.85 |
| Formula: | C16H19ClN2OS |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
BW-723C86 is an orally active and a selective 5-HT2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation[1][2][3][4][5][6].
In Vitro:BW-723C86 (1-100 nM) induces concentration-dependent relaxation of PGF2α-precontracted pig pulmonary artery with intact endothelium[1].
In Vivo:BW-723C86 (1-20 mg/kg, s.c., 30 min pre-test (grooming)) causes hyperphagia and decreased grooming in rats, with increasing the time spent in feeding behaviour[2].
BW-723C86 (10-30 mg/kg, i.p. 30 min pre-test) shows anxiolytic effects in rats via 5-HT2B receptor[3].
BW-723C86 (3-10 mg/kg, s.c. 30 min pretest) exerts an appreciable anxiolytic-like profile in rats, with increasing total social interaction[4].
BW-723C86 (5 mg/kg, p.o., 20 or 30 min before the liquid meal) inhibits liquid meal-induced gastric accommodation in normal Hartley guinea pigs[5].
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