Insulin glargine
CAS No. : 160337-95-1
| Size | Price | Stock |
|---|---|---|
| 100U | $80 | In-stock |
| 300U | $140 | Get quote |
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| Cat. No. : | HY-108719 |
| M.Wt: | 6062.89 |
| Formula: | C267H404N72O78S6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Insulin glargine is a long-acting insulin analog. Insulin glargine has the effect of lowering blood sugar and can be used in the research of diabetes. In addition, high doses of Insulin glargine can promote the proliferation of bladder cancer cells[1][2][3][4].
In Vitro:Insulin glargine (10-100 IU/L; 0-72 h) activates Akt in a PI3K-independent manner, thereby promoting the proliferation of bladder cancer cells[1].
In Vivo:Insulin glargine (2-12.5 IU/kg; subcutaneous injection; 3-12 months) does not present a carcinogenic risk in rodents[2].
Insulin glargine (450 mg/kg; subcutaneous injection; 6 months) has an improving effect in a mouse model of diabetes[3].
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