Iniparib


CAS No. : 160003-66-7

(Synonyms: BSI-201; NSC-746045; IND-71677)

160003-66-7
Price and Availability of CAS No. : 160003-66-7
Size Price Stock
5mg $59 In-stock
10mg $92 In-stock
25mg $205 In-stock
50mg $330 In-stock
100mg $462 In-stock
200mg $858 In-stock
500mg $1980 In-stock
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Cat. No. : HY-12015
M.Wt: 292.03
Formula: C7H5IN2O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 160003-66-7 :

Iniparib (BSI-201) is an irreversible inhibitor of PARP1, used in the research of triple negative breast cancer. IC50 & Target: PARP1[3] In Vitro: Iniparib nonselectively modifies cysteine-containing proteins in tumor cells[1]. Iniparib (100 μM) weakly inhibits SSB repair, and the inhibition can be reversed by knockdown of PARP1[2]. Iniparib in combination with cisplatin is cytotoxic to Myc/MDA-231 with EMT changes[3].

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