Mc-Val-Cit-PABC-PNP


CAS No. : 159857-81-5

(Synonyms: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate)

159857-81-5
Price and Availability of CAS No. : 159857-81-5
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250mg $80 In-stock
500mg $157 In-stock
1g $193 In-stock
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5g $673 In-stock
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Cat. No. : HY-20336
M.Wt: 737.76
Formula: C35H43N7O11
Purity: >98 %
Solubility: DMSO : ≥ 37 mg/mL
Introduction of 159857-81-5 :

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2]. In Vitro:ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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