ML401


CAS No. : 1597489-14-9

1597489-14-9
Price and Availability of CAS No. : 1597489-14-9
Size Price Stock
5mg $240 In-stock
10mg $390 In-stock
25mg $620 In-stock
50mg $850 In-stock
100mg $1100 In-stock
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Cat. No. : HY-116814
M.Wt: 419.74
Formula: C20H20BrClN2O
Purity: >98 %
Solubility: DMSO : 10.42 mg/mL (ultrasonic)
Introduction of 1597489-14-9 :

ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1]. IC50 & Target: IC50: 1.03 nM (EBI2)[1] In Vitro: ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM)[1]. In Vivo: ML401 shows very good stability in both human plasma and mouse plasma[1].

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