7-Fluorotryptamine (hydrochloride)


CAS No. : 159730-09-3

159730-09-3
Price and Availability of CAS No. : 159730-09-3
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1mg $30 In-stock
5mg $81 In-stock
10mg $130 In-stock
25mg $270 In-stock
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Cat. No. : HY-117295A
M.Wt: 214.67
Formula: C10H12ClFN2
Purity: >98 %
Solubility: DMSO : 116.67 mg/mL (ultrasonic)
Introduction of 159730-09-3 :

7-Fluorotryptamine hydrochloride is a potent agonist of GPRC5A. 7-Fluorotryptamine hydrochloride induces GPRC5A-mediated β-arrestin recruitment. 7-Fluorotryptamine hydrochloride can be used for research of immune and cancer signaling[1]. IC50 & Target:GPRC5A[1] In Vitro:7-Fluorotryptamine (100 μM) hydrochloride induces β-arrestin recruitment by GPRC5A in the PRESTO-Tango assay[1].
7-Fluorotryptamine (50 μM, 8 h) hydrochloride together with TNFα down-regulates some TNFα-induced genes (eg: IL41A, CXCL10, CSF2) in WT and GPRC5A-KO cells[1].
7-Fluorotryptamine (0-100 μM, 16 h) hydrochloride exhibits no toxicity for mammalian cells (HTLA, HT-29 cell)[1].

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