Paramethasone Acetate
CAS No. : 1597-82-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $185 | In-stock |
| 10mg | $280 | In-stock |
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| Cat. No. : | HY-107939 |
| M.Wt: | 434.50 |
| Formula: | C24H31FO6 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
Paramethasone Acetate is an orally active long-acting glucocorticoid. Paramethasone Acetate directly inhibits testicular aromatase, thereby reducing the synthesis of estradiol. Paramethasone Acetate suppresses the basal and midcycle luteinizing hormone surges in female animals and blocks estrogen synthesis. Paramethasone Acetate also decreases circulating levels of dihydrotestosterone, androstenedione and estradiol in male animals. Paramethasone Acetate inhibits cartilage degeneration and alleviates joint pathological damage in osteoarthritis models. Paramethasone Acetate can be used in research related to osteoarthritis and endocrinology[1][2]. In Vivo:Paramethasone Acetate (0.1 mg/kg; i.g.; 5 days per week; 5 weeks) significantly reduces the severity of surgically induced osteoarthritis in male New Zealand white rabbits[2].
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