Naphthol AS-MX phosphate


CAS No. : 1596-56-1

(Synonyms: NASTRp)

1596-56-1
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Cat. No. : HY-104067
M.Wt: 371.32
Formula: C19H18NO5P
Purity: >98 %
Solubility:
Introduction of 1596-56-1 :

Naphthol AS-MX phosphate (NASTRp) is a small molecule inhibitor of the CREB (cyclic adenosine phosphate reaction element binding protein)-CBP (CREB binding protein) transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation (IC50=3.701 μmol/L), colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer, especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis[1].

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