[Des-Arg9]-Bradykinin
CAS No. : 15958-92-6
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| Cat. No. : | HY-P0298 |
| M.Wt: | 904.02 |
| Formula: | C44H61N11O10 |
| Purity: | >98 % |
| Solubility: | 10 mM in H2O |
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors. IC50 & Target: Bradykinin (B1) receptor[1] In Vitro: The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
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