GR 55562 (dihydrochloride)


CAS No. : 159533-25-2

159533-25-2
Price and Availability of CAS No. : 159533-25-2
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Cat. No. : HY-101367A
M.Wt: 448.39
Formula: C23H27Cl2N3O2
Purity: >98 %
Solubility: H2O : 44.8 mg/mL (ultrasonic)
Introduction of 159533-25-2 :

GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1]. In Vivo:GR 55562 (0.1-10 μg/side) into accumbens subregions did not evoke cocaine-lever responding[1].
GR 55562 (0.1-10 μg/side) in the accumbens shell or core failed to modulate the discriminative stimulus effects of cocaine (5 mg/kg)[1].
GR 55562 (1 μg/side) significantly attenuated the enhancement of cocaine discrimination[1].

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