AZ191
CAS No. : 1594092-37-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $79 | In-stock |
| 10mg | $119 | In-stock |
| 25mg | $212 | In-stock |
| 50mg | $330 | In-stock |
| 100mg | $581 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12277 |
| M.Wt: | 429.52 |
| Formula: | C24H27N7O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL |
AZ191 is a potent inhibitor that selectively inhibits DYRK1B with IC50 of 17 nM[1].
IC50 & Target:IC50: 17 nM (DYRK1B)[1]
In Vitro: AZ191 (0.01-60μM; 5 days) inhibits SW872 and SW982 cell lines in dose-dependent manner with IC50s of 3.183 μM and 1.279 μM, respectively[2].
AZ191 (1-5 μM; 48 hours) down-regulates three anti-apoptotic proteins (Bcl-2, p21, and survivin) at higher concentrations[2].
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