MSN-50
CAS No. : 1592908-75-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $392 | In-stock |
| 5mg | $785 | In-stock |
| 10mg | $1250 | In-stock |
| 25mg | $2125 | In-stock |
| 50mg | $3190 | In-stock |
| 100mg | $4785 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-118948 |
| M.Wt: | 688.61 |
| Formula: | C36H38BrN3O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic) |
MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2]. IC50 & Target: Bax and Bak[1][2] In Vitro: MSN-50 (0~10 uM) inhibits dye release from liposomes in a concentration-dependent fashion. MSN-50 (0~40 uM) inhibits tBid/Bax-mediated MOMP (mitochondrial outer membrane permeabilization) in a concentration-dependent manner and shows concentration-dependent inhibition of Bak-mediated MOMP. MSN-50 inhibits both Bax and Bak after activation by either cBid or Bim. MSN-50 (5 μM; BMK cells) inhibits apoptosis induced by actinomycin D and staurosporin (STS)[1][2].
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