SW43
CAS No. : 1590379-85-3
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| Cat. No. : | HY-122224 |
| M.Wt: | 459.66 |
| Formula: | C27H45N3O3 |
| Purity: | >98 % |
| Solubility: |
SW43 is a Sigma-2 selective ligand and agonist. SW43 is an ideal molecule for the development of cancer-targeted drug compounds. SW43 conjugated with DOX-L-NETA (89Y) exhibits antitumor activity in a VX2 cancer liver tumor allograft rabbit model. SW 43 conjugated with SW IV-52s to form SW III-123 activates the NF-κB pathway, has potent cytotoxicity against ovarian cancer cell lines, and induces apoptosis[1][2].
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