GR231118
CAS No. : 158859-98-4
(Synonyms: 1229U91; GW1229)
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| Cat. No. : | HY-P1321 |
| M.Wt: | 2352.74 |
| Formula: | C110H170N34O24 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8)[1].
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