Chloralose


CAS No. : 15879-93-3

(Synonyms: α-Chloralose)

15879-93-3
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Cat. No. : HY-B1020
M.Wt: 309.53
Formula: C8H11Cl3O6
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 15879-93-3 :

Chloralose (α-Chloralose) is a central nervous system depressant. Chloralose (α-Chloralose) allosterically modulates GABAA receptor activity and binds to a site on the GABAA receptor complex, neurosteroid, and barbiturate sites[1]. IC50 & Target: EC50: 49 μM (GABA receptor)[1] In Vitro: Chloralose (α-Chloralose) activates the gama-aminobutyric acid (GABA)-induced chloride conductance of gama-aminobutyric acidA (GABAA) receptors expressed in Xenopus laevis oocytes with an EC50 value of 49 μM[1]

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