BMS-871
CAS No. : 1584631-89-9
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| Cat. No. : | HY-120372 |
| M.Wt: | 536.54 |
| Formula: | C29H27F3N4O3 |
| Purity: | >98 % |
| Solubility: |
BMS-871 is an orally active pan-Notch inhibitor with IC50 values of 4/1/4/3 nM for Notch1/2/3/4, respectively. BMS-871 significantly inhibited the proliferation of TALL-1 and MDA-MB-157 cells and demonstrated significant antitumor activity in T-acute lymphoblastic leukemia and triple-negative breast cancer xenograft models. BMS-871 can be used to study leukemia and breast cancer[1].
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- Cat. No.:
- HY-120372
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