Pumaprazole


CAS No. : 158364-59-1

(Synonyms: BY-841)

158364-59-1
Price and Availability of CAS No. : 158364-59-1
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5mg $250 In-stock
10mg $400 In-stock
25mg $810 In-stock
50mg $1300 In-stock
100mg $2100 In-stock
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Cat. No. : HY-19223
M.Wt: 338.40
Formula: C19H22N4O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 158364-59-1 :

Pumaprazole is a reversible proton pump antagonist. IC50 & Target: proton pump[1] In Vivo: Pumaprazole is a reversible proton pump antagonist. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compare to ranitidine. Pumaprazole displays identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23) and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1].

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