RIP2 kinase inhibitor 2


CAS No. : 1581270-11-2

1581270-11-2
Price and Availability of CAS No. : 1581270-11-2
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5mg $200 In-stock
10mg $320 In-stock
25mg $650 In-stock
50mg $1050 In-stock
100mg $1680 In-stock
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Cat. No. : HY-19761
M.Wt: 432.54
Formula: C21H28N4O4S
Purity: >98 %
Solubility: DMSO : 5 mg/mL (ultrasonic)
Introduction of 1581270-11-2 :

RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9. IC50 & Target: RIP2 Kinase[1] In Vitro: RIP2 kinase inhibitor 2 is a novel prodrug of a quinazolyl amine that inhibits RIP2 kinase. Receptor interacting protein-2 (RIP2) kinase is a TKL family serine/threonine protein kinase involved in innate immune signaling. Following activation, RIP2 kinase associates with NODI or NOD2 and appears to function principally as a molecular scaffold to bring together other kinases (TAK1, IKKα/β/γ) involved in NF-κB and mitogen-activated protein kinase activation[1].

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