Terodiline
CAS No. : 15793-40-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $385 | Get quote |
| 5mg | $950 | Get quote |
| 10mg | $1380 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-16489 |
| M.Wt: | 281.44 |
| Formula: | C20H27N |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Terodiline is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodiline also is a Ca2+ blocker. Terodiline acts as a treatment for urinary frequency and urge incontinence[1].
IC50 & Target: mAChR[1]
Ca2+ channel[1]
In Vivo: Terodiline (80 mg/kg; S.C.) is equipotent in inhibiting intravesical bladder pressure and carbachol-induced salivary secretion (ID50= 24 and 35 mg/kg, respectively), and in increasing pupil diameter (ED50=59 mg/kg)[1].
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