RO6889678


CAS No. : 1578153-27-1

1578153-27-1
Price and Availability of CAS No. : 1578153-27-1
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Cat. No. : HY-124364
M.Wt: 494.92
Formula: C21H20ClFN4O5S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1578153-27-1 :

RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation[1].

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