Cloprostenol isopropyl ester


CAS No. : 157283-66-4

157283-66-4
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Cat. No. : HY-100571
M.Wt: 466.99
Formula: C25H35ClO6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 157283-66-4 :

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2]. In Vivo:Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis[1].
Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey[2].

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