1-Ethynylnaphthalene
CAS No. : 15727-65-8
| Size | Price | Stock |
|---|---|---|
| 1g | $26 | In-stock |
| 5g | $62 | In-stock |
| 25g | $285 | In-stock |
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| Cat. No. : | HY-111430 |
| M.Wt: | 152.20 |
| Formula: | C12H8 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1. 1-Ethynylnaphthalene is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IC50 & Target: P450 1B1[1] In Vitro: 1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%[1].
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