Hemiasterlin


CAS No. : 157207-90-4

(Synonyms: (-)-Hemiasterlin; Milnamide B)

157207-90-4
Price and Availability of CAS No. : 157207-90-4
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5mg $765 In-stock
10mg $1230 In-stock
25mg $2460 In-stock
50mg $3950 In-stock
100mg $6320 In-stock
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Cat. No. : HY-117371
M.Wt: 526.71
Formula: C30H46N4O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 157207-90-4 :

Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effects. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs)[1]. In Vitro:Hemiasterlin is an antimitotic agent by disrupting microtubule dynamics causing mitotic arrest and cell death with low- to sub-nanomolar potencies against several cancer cell lines[1].

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