(R)-Methanandamide


CAS No. : 157182-49-5

(Synonyms: AM-356)

157182-49-5
Price and Availability of CAS No. : 157182-49-5
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Cat. No. : HY-101389
M.Wt: 361.56
Formula: C23H39NO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 157182-49-5 :

(R)-Methanandamide (AM-356), an analog of the endocannabinoid ligand Anandamide, is a potent CB1 agonist with a Ki of 20 nM. (R)-Methanandamide also activates vanilloid (TRPV1) receptors[1][2]. In Vitro: The endogenous cannabinoid (R)-Methanandamide exerts differential anti- and pronociceptive effects by activating both cannabinoid (CB1) and vanilloid (TRPV1) receptors of nociceptive primary afferents[2].

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