U-89843A (hydrochloride)


CAS No. : 157013-85-9

(Synonyms: PNU-89843 (hydrochloride))

157013-85-9
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Cat. No. : HY-103497
M.Wt: 321.85
Formula: C16H24ClN5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 157013-85-9 :

U-89843A (PNU-89843) hydrochloride is a GABAA receptors positive allosteric modulator (PAM). U-89843A hydrochloride enhances GABA-induced Cl- currents in the α1β2γ2, α3β2γ2 and α6β2γ2 subtypes. U-89843A hydrochloride shows antioxidant and sedative effects[1][2]. IC50 & Target:GABAA receptor[1]

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