Pyrantel
CAS No. : 15686-83-6
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| Cat. No. : | HY-12641A |
| M.Wt: | 206.31 |
| Formula: | C11H14N2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2]. IC50 & Target:Parasites[1][2]. In Vitro: Pyrantel (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity[1][2]. In Vivo: Pyrantel (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%[2].
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