Ryanodine
CAS No. : 15662-33-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $500 | In-stock |
| 5mg | $1650 | In-stock |
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| Cat. No. : | HY-103306 |
| M.Wt: | 493.55 |
| Formula: | C25H35NO9 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. IC50 & Target:Ryanodine receptor[1] In Vivo: Ryanodine (100-5000 nM, 30-120 mintutes) irreversibly depresses twitch and tetanic tension of both fast and slow muscle in a dose-related manner[1].
At concentrations above 250 nM, ryanodine induces a slowly developing, dose dependent contracture which could not be blocked by 5 mMCo2+[1].
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