PBB3
CAS No. : 1565796-97-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $360 | In-stock |
| 10mg | $590 | In-stock |
| 25mg | $1180 | In-stock |
| 50mg | $1900 | In-stock |
| 100mg | $3050 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-114616 |
| M.Wt: | 309.39 |
| Formula: | C17H15N3OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PBB3 is a tracer of tau PET. PBB3 can be used to detect levels of tau protein in Alzheimer's disease and non-Alzheimer's disease[1].
In Vitro:PBB3 (56.5 µM) labels Alzheimer's disease patient-originated brain pathological changes by fluorescent labeling[1].
PBB3 (56.5 µM) labels neuropil threads and plaque neurites in hippocampal derived from an Alzheimer’s disease patient[1].
PBB3 bound
to primitive plaques, which is accumulation ofabnormally swollen neurites without cores of
extracellular amyloid[1].
PBB3 clearly detects dystrophic neurites in
brains of Alzheimer's disease and diffuse neurofibrillary tangles with calcification
characterized by accumulation of all six tau isoforms[1].
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