H-HoArg-OH


CAS No. : 156-86-5

156-86-5
Price and Availability of CAS No. : 156-86-5
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Cat. No. : HY-W008385
M.Wt: 188.23
Formula: C7H16N4O2
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic);DMSO : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 156-86-5 :

H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase. IC50 & Target: Alkaline phosphatase[1]. In Vitro: It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase[1]. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease[2].

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