LL-37, human
CAS No. : 154947-66-7
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| 5mg | $260 | In-stock |
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| Cat. No. : | HY-P1222 |
| M.Wt: | 4493.26 |
| Formula: | C205H340N60O53 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic) |
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing[1][2][3]. In Vitro: LL-37, human (1-20 μg/mL; 24 h) affects HCECs migration[2]. LL-37, human (0.0001-5 μg/mL;6-24 h) affects cytokine secretion in HCECs[2]. LL-37, human (1-100 μg/mL; 24 h) shows dose-dependently cytotoxic to HCECs at concentrations over 10 μg /mL[2]. In Vivo: LL-37, human (0.4-2.0 mg/kg; intratracheal injection once) ameliorates MRSA-induced pneumonia of mice[3].
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