Autotaxin modulator 1


CAS No. : 1548743-69-6

1548743-69-6
Price and Availability of CAS No. : 1548743-69-6
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Cat. No. : HY-12812
M.Wt: 543.54
Formula: C28H31F6NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1548743-69-6 :

Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer[1]. IC50 & Target: Autotaxin[1] In Vitro: Autotaxin, a novel motility-stimulating protein, is a secreted glycoprotein widely present in biological fluids, including blood, cancer ascites, synovial, pleural and cerebrospinal fluids, originally isolated from the supernatant of melanoma cells as an autocrine motility stimulation factor[1].
Autotaxin is a member of the ectonucleotide pyrophosphatase/phosphodiesterase family of ectoenzymes (E-NPP) that hydrolyze phosphodiesterase (PDE) bonds of various nucleotides and derivatives[1].

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