APC-6860


CAS No. : 154628-42-9

154628-42-9
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Cat. No. : HY-114015
M.Wt: 302.13
Formula: C9H7IN2S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 154628-42-9 :

APC-6860 is a trypsin-like serine proteases inhibitor with ki values of 0.21 and 0.44 μM for uPA and trypsin, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has ki values of 0.1 and 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer[1][2]. In Vitro: APC-6860 (compound 2) inhibits urokinases in MiaPaCa-2 and Lewis Lung Carcinoma cells with IC50s of 1.4 and 3.1 μM, respectively[2].

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