COX/5-LO-IN-1
CAS No. : 154355-75-6
(Synonyms: Atreleuton analog)
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| Cat. No. : | HY-U00347 |
| M.Wt: | 318.37 |
| Formula: | C16H15FN2O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor of cylooxygenase and 5-lipoxygenase (5-LO), used for the research of inflammatory and allergic disease states. In Vitro: COX/5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4, and E4 and cyclooxygenase products such as prostaglandins and thromboxane and are useful in the treatment of inflammatory and allergic disease states[1]. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase, with IC50 of 0.2 μM in human whole blood[2].
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