6-Thioguanine (Standard)
CAS No. : 154-42-7
(Synonyms: Thioguanine (Standard); 2-Amino-6-purinethiol (Standard))
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| Cat. No. : | HY-13765R |
| M.Wt: | 167.19 |
| Formula: | C5H5N5S |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (59.81 mM; Need ultrasonic and warming) |
6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. IC50 & Target:IC50: 25 μM (PLpros), 40 μM (Recombinant human USP2)[3]
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