YM114
CAS No. : 153608-99-2
(Synonyms: KAE-393)
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| Cat. No. : | HY-106909A |
| M.Wt: | 303.79 |
| Formula: | C16H18ClN3O |
| Purity: | >98 % |
| Solubility: |
YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1].
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