Carbazeran (citrate)


CAS No. : 153473-94-0

153473-94-0
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Cat. No. : HY-108680
M.Wt: 552.53
Formula: C24H32N4O11
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 153473-94-0 :

Carbazeran (citrate), a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran (citrate) can be used for the research of metabolic disease[1]. IC50 & Target: phosphodiesterase[1] In Vivo: Carbazeran (10 mg/kg; p.o.) (citrate) of the unmetabolized in samples from humanized-liver mice, the mean plasma concentrations are lower than in those from control mice for 0.5~4 hours after oral administration[1].
Oral administration of carbazeran (citrate) to guinea pigs has reportedly resulted in large kinetic deuterium isotope effects on the AUC and Cmax, without a change of systemic half-life[1].

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