Fexofenadine (hydrochloride)
CAS No. : 153439-40-8
(Synonyms: MDL-16455 (hydrochloride); Terfenadine carboxylate (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $55 | In-stock |
| 25mg | $95 | In-stock |
| 50mg | $132 | In-stock |
| 100mg | $220 | In-stock |
| 500mg | $550 | In-stock |
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| Cat. No. : | HY-B0801A |
| M.Wt: | 538.12 |
| Formula: | C32H40ClNO4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research[1][2][3].
IC50 & Target:H1R[1]
In Vitro:Fexofenadine (1-100 µM; 1 h) inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner[2].
Fexofenadine (1-100 µM; 1 h) blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts, but shows no effect on either pERK or pJNK[2].
In Vivo:Fexofenadine hydrochloride (oral administration; 5-20 mg/kg; once daily; 3 w) suppresses both eosinophilia and systemic anaphylaxis in C57BL/6 mice infected with T. spiralis[1].
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