CAS No. : 1532533-69-9
(Synonyms: TGR-1202 R-enantiomer; RP5264 R-enantiomer)
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| Cat. No. : | HY-12279F |
| M.Wt: | 571.55 |
| Formula: | C31H24F3N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202. In Vitro: Umbralisib R-enantiomer (TGR-1202 R-enantiomer) (Formula A) exhibits a 50% inhibitory concentration (IC50) with respect to the δ type PI3-kinase that is at least 20-fold lower than the inhibitor's IC50 with respect to the rest of the other PI3K isoforms (i.e., a, β, and γ)[1].
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