Umbralisib R-enantiomer


CAS No. : 1532533-69-9

(Synonyms: TGR-1202 R-enantiomer; RP5264 R-enantiomer)

1532533-69-9
Price and Availability of CAS No. : 1532533-69-9
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1mg $240 In-stock
5mg $580 In-stock
10mg $850 In-stock
25mg $1500 In-stock
50mg $1950 In-stock
100mg $2530 In-stock
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Cat. No. : HY-12279F
M.Wt: 571.55
Formula: C31H24F3N5O3
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 1532533-69-9 :

Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202. In Vitro: Umbralisib R-enantiomer (TGR-1202 R-enantiomer) (Formula A) exhibits a 50% inhibitory concentration (IC50) with respect to the δ type PI3-kinase that is at least 20-fold lower than the inhibitor's IC50 with respect to the rest of the other PI3K isoforms (i.e., a, β, and γ)[1].

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