Glycolithocholic acid 3-sulfate
CAS No. : 15324-64-8
(Synonyms: Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG)
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| 10mg | $450 | In-stock |
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| Cat. No. : | HY-113074 |
| M.Wt: | 513.69 |
| Formula: | C26H43NO7S |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease[1][2]. In Vitro:Glycolithocholic acid 3-sulfate (100 μg/mL) protects MT-4 cells against HIV-1-induced cytopathogenicity[1]. Glycolithocholic acid 3-sulfate (200 μg/mL) shows no toxicity for host cells[1]. Glycolithocholic acid 3-sulfate inhibits HIV-1 antigen expression in HIV-1-infected CEM cells[1]. In Vivo:Glycolithocholic acid 3-sulfate (24 μmoL /100 g; i.v., once) induces intrahepatic cholestasis and increases biliary cholesterol secretion in male Wistar rats with bile fistula[2].
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