BMS 182874
CAS No. : 153042-42-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $68 | In-stock |
| 10mg | $111 | In-stock |
| 25mg | $191 | In-stock |
| 50mg | $272 | In-stock |
| 100mg | $375 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-118497 |
| M.Wt: | 345.42 |
| Formula: | C17H19N3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
BMS 182874 is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].
In Vitro:BMS-182874 (dimethyla minoanalogue 11) is an antagonist of the ETA ,with IC50 value of 0.150 μM and Ki of 0.055 μM in vsm-A10 cells, and with a KB value of 0.520 μM in rabbit carotid artery rings[1].
In Vivo:BMS 182874 (100 μM/kg, p.o.; a single oral) makes arterial pressure slowly fell by 25% from a control level. After dosing for 12 and 24 h makes arterial pressure is still 12% below the control level[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- BMS 182874
- Cat. No.:
- HY-118497
- Quantity:
Your information is safe with us.