L-736380
CAS No. : 152885-49-9
(Synonyms: L-736360)
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| Cat. No. : | HY-118665 |
| M.Wt: | 487.56 |
| Formula: | C25H29N9O2 |
| Purity: | >98 % |
| Solubility: |
L-736380 is a high affinity CCK-B (cholecystokinin B receptor) receptor antagonist, with IC50 values of 0.054 nM and 400 nM for CCK-B and CCK-A, respectively. L-736380 dose-dependently inhibits gastric acid secretion in anesthetized rats (ID50, 0.064 mg/kg) and ex vivo binding of [125I]CCK-8S in BKTO mice brain membranes (ED50, 1.7 mg/kg)[1].
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