rac-Olodanrigan
CAS No. : 152362-51-1
(Synonyms: rac-EMA401; rac-PD-126055; EMA400)
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| Cat. No. : | HY-19202 |
| M.Wt: | 507.58 |
| Formula: | C32H29NO5 |
| Purity: | >98 % |
| Solubility: |
rac-Olodanrigan (rac-EMA401; EMA400) is a racemic mixture of the S-enantiomer (EMA401; HY-13106) and R-enantiomer (EMA402). rac-Olodanrigan is a potent and selective AT2 receptor antagonist with IC50s of 75.2 nM and 2918 nM for AT2R and AT1R, respectively. rac-Olodanrigan evokes dose-dependent relief of mechanical allodynia in the ipsilateral hind paws of rats with a chronic constriction injury (CCI) of the sciatic nerve[1].
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